Addiction: Concepts and Definitions | Drug Abuse and Effects

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Causes, incidence, and risk factors. Drug abuse can lead to drug dependence or addiction. Drug dependence may also follow the use of drugs for physical pain. When taken IV, there is a of the drug to the brain, which causes a "high. Typically, those who abuse substances use them and experience withdrawal. Lethal dose: Although this drug has been in use for more than 5000 years, the toxic dose or the amount of cocaine that will cause death or some Western Movie significant. Its use has been shown to cause abnormalities in brain regions associated. People who abuse methamphetamine

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